Basic Information
VIS ID
TVIS44021840
Fusion event
HTLV-1-SLC44A3-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
95232937/94767381 (Hg38)
End
95232937/94767381 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA1M
Target gene
SLC44A3-AS1
Nearest miRNA
hsa-mir-101-1/Upstream/223602; hsa-mir-11399/Downstream/3277861;
Nearest TSS
ENST00000473358/Upstream/175084; ENST00000422520/Downstream/52961;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/225298, chr1-CpG: 70/Downstream/52665
Upstream sequence
atttccttttctataaaacaaaaggtcatgagatcccttctagctGGAGAGGCTATTTCTGGCTACCTAGAGTTGTCACTTCTGGGCAAACCTGGTATTG
Downstream sequence
CTGCCCTCTTTGTTGTTTCCATTTTTTATTTCCCTCCTCCCTCCTTTTTTTCCACAGAGTACCTACTATGATCTCAGAacagtccctgccctcaagcact
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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