VISDB Viral Integration Site DataBase

VIS ID

TVIS44021843

Fusion event

HTLV-1-PTBP2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr1

Cytoband

p21.3

Reference genome

Start

End

97241271/96775715 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-133b ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-223-3p ; hsa-mir-590-3p ; hsa-mir-4775 ; hsa-mir-6885-3p ; hsa-mir-1273e ; hsa-mir-4670-3p ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-219b-3p ; hsa-mir-4740-3p ; hsa-mir-302f ; hsa-mir-548q ; hsa-mir-548ag ; hsa-mir-576-5p ; hsa-mir-4263 ; hsa-mir-6509-5p ; hsa-mir-548aw ; hsa-mir-1273g-5p ; hsa-mir-203a-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4735-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548n ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-7847-3p ; hsa-mir-6880-5p ; hsa-mir-6851-5p ; hsa-mir-3689d ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-4768-3p ; hsa-mir-95-5p ; hsa-mir-654-3p ; hsa-mir-338-5p ; hsa-mir-548at-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-550b-2-5p ; hsa-mir-6743-3p ; hsa-mir-7160-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6125 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p

Nearest miRNA

hsa-mir-101-1/Upstream/2231936; hsa-mir-11399/Downstream/1269527;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/53452, chr1-CpG: 47/Downstream/1144918

Upstream sequence

ctgggtaattatttcacagagatgtccaatttgtggtattttatggagctttatacttaggttttgtgtccttttgtgtgtgtgtgtaatattttgataa

Downstream sequence

gaagtttTATTAAAATCTAGGTTTGCAAGCCAACACTGCTCCATGAATTATAAGAAAAAATATATGAAGTCATTAAAAATGAAATCATAAAGAAATGTAT