Basic Information
VIS ID
TVIS44021854
Fusion event
HTLV-1-SH3RF3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q13
Reference genome
GRCh37/hg19
Start
109961316/109344860 (Hg38)
End
109961316/109344860 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
SH3RF3
Nearest miRNA
hsa-mir-1285-2/Upstream/31235; hsa-mir-10b/Downstream/725101;
Nearest TSS
ENST00000437798/Upstream/215512; ENST00000356454/Downstream/222993;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/214483, chr2-CpG: 246/Downstream/268469
Upstream sequence
GATGACTGAAGGTCCTTGCCGAGCAGCTGAGTGGGGATTTCATGGCCAGAGGAGGTAGGGCTGGAGGGACAGACAGCCTCTAGGAGCTTGCAGATGTCCA
Downstream sequence
GCAGAGCCGTCAAGCAGGCATCTGGGTTCACATCAAGTCCCATGATCAGAGGGGACATCACAGGCACAGGTTGATTTGAGAGCCACTGGCACAGAGGCAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate