Basic Information
VIS ID
TVIS44021857
Fusion event
HTLV-1-DPP10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
115254979/114497402 (Hg38)
End
115254979/114497402 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
DPP10
Nearest miRNA
hsa-mir-1285-2/Upstream/776034; hsa-mir-10b/Downstream/12926135;
Nearest TSS
ENST00000437798/Upstream/35799; ENST00000492708/Downstream/336146;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/517290, chr2-CpG: 51/Downstream/164749
Upstream sequence
gtgtatacatgtacatgtatacgtgtatacatgtacatatacatacacatgtacatatacatacacatgtacatatacatatacatacacatacatatac
Downstream sequence
atatacacatacatatgcatctatatatatatgcatatatatagatgcatctattttatagatgcatctaagaatagggtcAGTGGTGAACCATAAACTA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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