VISDB Viral Integration Site DataBase

VIS ID

TVIS44021858

Fusion event

HTLV-1-E2F6 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

p25.1

Reference genome

Start

End

11603535/11463409 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193a-3p ; hsa-mir-137 ; hsa-mir-124-3p ; hsa-let-7b-5p ; hsa-mir-28-5p ; hsa-mir-151a-5p ; hsa-mir-193b-3p ; hsa-mir-98-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-759 ; hsa-mir-5582-5p ; hsa-mir-4797-5p ; hsa-mir-3646 ; hsa-mir-1252-3p ; hsa-mir-548g-3p ; hsa-mir-6766-5p ; hsa-mir-548av-3p ; hsa-mir-331-5p ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-6090 ; hsa-mir-6827-5p ; hsa-mir-4468 ; hsa-mir-6081 ; hsa-mir-299-3p ; hsa-mir-4501 ; hsa-mir-4678 ; hsa-mir-5591-3p ; hsa-mir-4650-3p ; hsa-mir-202-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-let-7i-5p ; hsa-mir-4500 ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7a-5p ; hsa-mir-4458 ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-mir-1269a ; hsa-mir-1269b ; hsa-mir-1288-3p ; hsa-mir-185-5p ; hsa-mir-2355-3p ; hsa-mir-3135b ; hsa-mir-345-5p ; hsa-mir-3616-3p ; hsa-mir-421 ; hsa-mir-4306 ; hsa-mir-4487 ; hsa-mir-4513 ; hsa-mir-4515 ; hsa-mir-4529-3p ; hsa-mir-4644 ; hsa-mir-4709-5p ; hsa-mir-4740-5p ; hsa-mir-5009-5p ; hsa-mir-5192 ; hsa-mir-548aa ; hsa-mir-548ap-3p ; hsa-mir-548as-3p ; hsa-mir-548at-3p ; hsa-mir-548ay-3p ; hsa-mir-548t-3p ; hsa-mir-6758-5p ; hsa-mir-676-3p ; hsa-mir-6771-3p ; hsa-mir-6809-5p ; hsa-mir-6855-3p ; hsa-mir-6856-5p ; hsa-mir-8058

Nearest miRNA

hsa-mir-4261/Upstream/1270738; hsa-mir-10b/Downstream/77196;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/117982, chr2-CpG: 83/Downstream/2208

Upstream sequence

ctttacgatgacctaattcccccgaaggagtaggattttctcttatttatgattttcttaataacattttcttttctttagctactttactataagaaaa

Downstream sequence

cagtaactaatacatataaatacaaaatatgtgtcaattaactgtttacggtatcagtaaggcttccagcaaacagtaaagttttgggggaatcaaagtt