Basic Information
VIS ID
TVIS44021860
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.1
Reference genome
GRCh37/hg19
Start
117367292/116609716 (Hg38)
End
117367292/116609716 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA2S
Nearest miRNA
hsa-mir-1285-2/Upstream/2888348; hsa-mir-10b/Downstream/10813821;
Nearest TSS
ENST00000437798/Upstream/795053; ENST00000489933/Downstream/1194458;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/1446527, chr2-CpG: 48/Downstream/1204820
Nearby gene
DPP10(+764966) ;
Upstream sequence
GTTCTTAAATCATAGAATAATAATGAACTCGCCATGATTTATCTACATGTATTTCATTCGAATCATATCCAGCATTCAAACCCAAGATTAGAATATGCGT
Downstream sequence
GTTTCTTCCTTCAAACTGCAGATCCAGTTCAAGCTTCACTATAAATTCTACCTGGCTACTTGTTTCTACATTGCTAACTCCTTTTTTTTCCCTCAAAGCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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