Basic Information
VIS ID
TVIS44021871
Fusion event
HTLV-1-LOC105373592 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
122884385/122126809 (Hg38)
End
122884385/122126809 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373592
Nearest miRNA
hsa-mir-1285-2/Upstream/8405441; hsa-mir-10b/Downstream/5296728;
Nearest TSS
ENST00000437798/Upstream/336317; ENST00000435441/Downstream/938512;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/370859, chr2-CpG: 79/Downstream/1897866
Nearby gene
TSN(+358957) ;
Upstream sequence
agactagttgaatgttgtgaccaaaatgctgatagtgatatggacaatgaagtccaggctgaggtggtctcagatgcagaagaggaacttactgggaact
Downstream sequence
ggagtaaaggtcactcttgctatgctttagcacagagactggtgacattgtgtccctgctctagggatctatgggacgttgaacttgatactggtgattt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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