Basic Information
VIS ID
TVIS44021875
Fusion event
HTLV-1-LOC105373608 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q14.3
Reference genome
GRCh37/hg19
Start
128214380/127456804 (Hg38)
End
128214380/127456804 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373608
Nearest miRNA
hsa-mir-1285-2/Upstream/33186; hsa-mir-10b/Downstream/4034356;
Nearest TSS
ENST00000437798/Upstream/1296; ENST00000598696/Downstream/6838;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/28010, chr2-CpG: 75/Downstream/69198
Nearby gene
IWS1(-24003) ;
Upstream sequence
caccgATATGCGCATCtttttttttttttttttttttttttttttttttgagatggagtcttgctctgtcgccaggctggagtgcagtggcgtgataccg
Downstream sequence
gctcactgcaatctccatctcctgggttcaagcgattcccctgcctcagcctccccgagtagctgtgactccaggcacgcaccactatgcccggctaatt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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