Basic Information
VIS ID
TVIS44021879
Fusion event
HTLV-1-LOC105373618 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
131148999/130391426 (Hg38)
End
131148999/130391426 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC105373618
Nearest miRNA
hsa-mir-1285-2/Upstream/2967808; hsa-mir-10b/Downstream/1099734;
Nearest TSS
ENST00000437798/Upstream/18818; ENST00000281882/Downstream/117861;
Nearest CpG islands
chr2-CpG: 63/Target, None/Upstream, None/Downstream
Nearby gene
PTPN18(+16017) ;
Upstream sequence
GGGGCGGGGCGGGGCCAGAGTGACAGGCAGCCCTGCGGGCCCCTGGCCCCTCCCCACAGCCCCTGAGACTTGTGCGGCCCGCAGGAATCTTCTGGCGGCC
Downstream sequence
ACCCGGTTCGCCGGCAGCACTGTATCAGTTTCTACATGGCTCCTCTCCCAGCCCCTTACGTGGCTTATTTCGTGTCAATTCTAGGGAGGTTCTACCGTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate