Basic Information
VIS ID
TVIS44021882
Fusion event
HTLV-1-MGAT5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
End
134909797/134152226 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/25034; hsa-mir-10b/Downstream/705594;
Nearby gene
MIR3679(+25034) ;
Upstream sequence
CACTCATCCCCTCTGGGACCCACCCACCACCATGGGACCTCATTCACTCACACCCTATGGGACCTGCCCACCGCCATGGGAACTCACTCACACCCTATGG
Downstream sequence
GACCCGCTTACCACCATGGGACCCGCTTACCACCATGGGACCTCACGCCCTATGGGACCTGCTTACCACCATGGGACCCGCTTATCACTCACGCCCTATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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