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TVIS44021882
Basic Information
VIS ID
TVIS44021882
Fusion event
HTLV-1-MGAT5 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
134909797/134152226 (Hg38)
End
134909797/134152226 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
MGAT5
miRNAs that regulate target gene
hsa-mir-502-3p
;
hsa-mir-769-5p
;
hsa-mir-181a-5p
;
hsa-mir-23c
;
hsa-mir-23b-3p
;
hsa-mir-23a-3p
;
hsa-mir-130a-5p
;
hsa-mir-7847-3p
;
hsa-mir-6894-5p
;
hsa-mir-765
;
hsa-mir-7154-3p
;
hsa-mir-766-5p
;
hsa-mir-5189-3p
;
hsa-mir-6511b-3p
;
hsa-mir-6511a-3p
;
hsa-mir-3680-5p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-7850-5p
;
hsa-mir-4529-3p
;
hsa-mir-4520-2-3p
;
hsa-mir-8058
;
hsa-mir-5009-5p
;
hsa-mir-1269b
;
hsa-mir-1269a
;
hsa-mir-3121-5p
;
hsa-mir-4279
;
hsa-mir-6881-3p
;
hsa-mir-5581-3p
;
hsa-mir-1236-3p
;
hsa-mir-6845-3p
;
hsa-mir-3667-3p
;
hsa-mir-877-3p
;
hsa-mir-5685
;
hsa-mir-6872-3p
;
hsa-mir-4690-3p
;
hsa-mir-6743-5p
;
hsa-mir-4688
;
hsa-mir-6768-5p
;
hsa-mir-5681a
;
hsa-mir-6891-3p
;
hsa-mir-6072
;
hsa-mir-6738-3p
;
hsa-mir-5001-3p
;
hsa-mir-6886-3p
;
hsa-mir-938
;
hsa-mir-6505-3p
;
hsa-mir-324-3p
;
hsa-mir-1913
;
hsa-mir-539-3p
;
hsa-mir-485-3p
;
hsa-mir-3941
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-629-3p
;
hsa-mir-29b-2-5p
;
hsa-mir-6855-5p
;
hsa-mir-3170
;
hsa-mir-519e-5p
;
hsa-mir-515-5p
;
hsa-mir-6742-5p
;
hsa-mir-92a-2-5p
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-193b-5p
;
hsa-mir-3925-3p
;
hsa-mir-766-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4695-5p
;
hsa-mir-3155a
;
hsa-mir-3155b
;
hsa-mir-4438
;
hsa-mir-484
Nearest miRNA
hsa-mir-1285-2/Upstream/25034; hsa-mir-10b/Downstream/705594;
Nearest TSS
ENST00000437798/Upstream/32044;
ENST00000488365/Downstream/100878;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/30629
,
chr2-CpG: 57/Downstream/39270
Nearby gene
MIR3679
(+25034) ;
Upstream sequence
CACTCATCCCCTCTGGGACCCACCCACCACCATGGGACCTCATTCACTCACACCCTATGGGACCTGCCCACCGCCATGGGAACTCACTCACACCCTATGG
Downstream sequence
GACCCGCTTACCACCATGGGACCCGCTTACCACCATGGGACCTCACGCCCTATGGGACCTGCTTACCACCATGGGACCCGCTTATCACTCACGCCCTATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Sample Information
×
Sample name
HAM/TSP#3
Sample type
Nontumor
Gender
Female
CpG Island Information
×
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