Basic Information
VIS ID
TVIS44021885
Fusion event
HTLV-1-LOC112268426 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
136854984/136097414 (Hg38)
End
136854984/136097414 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2F
Target gene
LOC112268426
Nearest miRNA
hsa-mir-128-1/Upstream/431936; hsa-mir-10b/Downstream/4489212;
Nearest TSS
ENST00000437798/Upstream/19522; ENST00000472720/Downstream/18829;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/111389, chr2-CpG: 156/Downstream/19102
Nearby gene
CXCR4(-16935) ;
Upstream sequence
ATTATCAGTGTCTGATCCTTGTCTTAGTGTCTCAGCATATTATAATATTGTATACAATGAGccatccttctggaaatgctgtctgctcttggcttccata
Downstream sequence
gaccctacatttttggattttcttgagcttcactgtcttctcagtcccctttgcaagttcatcctcctccactcagcctctaagagttagaagcactcag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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