VISDB Viral Integration Site DataBase

VIS ID

TVIS44021917

Fusion event

HTLV-1-METTL8 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q31.1

Reference genome

Start

End

172174764/171318254 (Hg38)

Orient

-

Location type

UTR3

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-29b-2-5p ; hsa-mir-5706 ; hsa-mir-4782-5p ; hsa-mir-516b-5p ; hsa-mir-1299 ; hsa-mir-6128 ; hsa-mir-875-3p ; hsa-mir-129-5p ; hsa-mir-3149 ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-513a-5p ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-4524a-3p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-4735-5p ; hsa-mir-6823-5p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4524b-3p ; hsa-mir-590-3p ; hsa-mir-4668-5p ; hsa-mir-559 ; hsa-mir-4803 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-548n ; hsa-mir-6741-5p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-4252 ; hsa-mir-6776-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6742-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-5193 ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-5007-3p ; hsa-mir-5701 ; hsa-mir-4795-3p ; hsa-mir-6853-3p ; hsa-mir-1206 ; hsa-mir-126-5p ; hsa-mir-656-3p ; hsa-mir-193a-5p

Nearest miRNA

hsa-mir-128-1/Upstream/2735236; hsa-mir-10b/Downstream/3849379;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/156904, chr2-CpG: 104/Downstream/115600

Upstream sequence

TATAAATGAAGATGCAACTGTTATTTTACTTCTATTTATATTTATAACTACACCAAAGCCATCTTGCGGGTACCTTTGCGCCTCTCAAATCCCCAACCAT

Downstream sequence

ATTCCAAGAAACCGTATTCCAAGAAATGCTCAACATTTCATGCCTGAATTGGTATTAATGTGGCATTAATGTACATACAATGTTTTAAATAACGATGTTT