Basic Information
VIS ID
TVIS44021925
Fusion event
HTLV-1-LOC105373456 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p24.2
Reference genome
GRCh37/hg19
Start
18819645/18638379 (Hg38)
End
18819645/18638379 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2C
Target gene
LOC105373456
Nearest miRNA
hsa-mir-3125/Upstream/5900935; hsa-mir-10b/Downstream/710050;
Nearest TSS
ENST00000437798/Upstream/48807; ENST00000431697/Downstream/146428;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/53465, chr2-CpG: 71/Downstream/709342
Nearby gene
NT5C1B-RDH14(-48799) ;
Upstream sequence
gggtgtgtctgtgagggtgttgccaaagaagattaacatttgagtcagtggactgggaaaggcacacccaccctcaatatgggtgggcacaatcaaatca
Downstream sequence
gctgccagcatggcccgaataaaaagcaggcagaaaaacgtgcaaagactagactggctgaatgttctggcctccatctttctcccatgctggatgcttc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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