Basic Information
VIS ID
TVIS44021934
Fusion event
HTLV-1-chr2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
208392611/207527887 (Hg38)
End
208392611/207527887 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA2I
Nearest miRNA
hsa-mir-10b/Upstream/258463; hsa-mir-1244-1/Downstream/226920;
Nearest TSS
ENST00000437798/Upstream/267442; ENST00000414681/Downstream/1850;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/361134, chr2-CpG: 174/Downstream/1344
Nearby gene
CREB1(+2005) ;
Nearest cancer related gene
CREB1(OG, +2005) ;
Upstream sequence
accagggactatgggaggagcgttttgaaggaattatgatatacgggttgagtttgaaatgccctaagtcatccaaatgaaagtgtaccaaaggcagtat
Downstream sequence
gctgggaactatgaatgtaggattccagagcaagatctaggcttgagttatggattgaagagtctttgacagagggtatttgatgctgctgggagagcat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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