VISDB Viral Integration Site DataBase

VIS ID

TVIS44021951

Fusion event

HTLV-1-SP140L integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr2

Cytoband

q37.1

Reference genome

Start

End

231237588/230372873 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-4298 ; hsa-mir-1302 ; hsa-mir-4684-5p ; hsa-mir-585-5p ; hsa-mir-3649 ; hsa-mir-711 ; hsa-mir-942-5p ; hsa-mir-3189-3p ; hsa-mir-212-5p ; hsa-mir-501-5p ; hsa-mir-500b-5p ; hsa-mir-362-5p ; hsa-mir-1273h-5p ; hsa-mir-1468-3p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3190-5p ; hsa-mir-340-3p ; hsa-mir-34b-3p ; hsa-mir-3606-5p ; hsa-mir-3612 ; hsa-mir-3614-5p ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3926 ; hsa-mir-3929 ; hsa-mir-4329 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4497 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4728-5p ; hsa-mir-4768-3p ; hsa-mir-4786-5p ; hsa-mir-485-5p ; hsa-mir-548aj-5p ; hsa-mir-548aw ; hsa-mir-548c-3p ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548s ; hsa-mir-548x-5p ; hsa-mir-6500-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6771-3p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6788-5p ; hsa-mir-6799-5p ; hsa-mir-6827-3p ; hsa-mir-6849-3p ; hsa-mir-6883-5p ; hsa-mir-6884-5p ; hsa-mir-7106-5p ; hsa-mir-887-5p

Nearest miRNA

hsa-mir-10b/Upstream/2900686; hsa-mir-1244-1/Downstream/989835;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/304039, chr2-CpG: 125/Downstream/339721

Upstream sequence

ataaaaatctagaaatgatgaagtttagtgaggaagctatgtcaaaagttgacataggctgaaaattaggccttttgcagaaaataattggccaagttat

Downstream sequence

gaatgcaaaggaaaagttcttgaaggaaattaaaagtgctactccagtgaacactttaatgataaagcagaacagtcttattgctgatgtggagaaagtt