Basic Information
VIS ID
TVIS44021963
Fusion event
HTLV-1-LINC01237 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q37.3
Reference genome
GRCh37/hg19
Start
242961999/242019848 (Hg38)
End
242961999/242019848 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA2J
Target gene
LINC01237
Nearest miRNA
hsa-mir-10b/Upstream/541866;
Nearest TSS
ENST00000437798/Upstream/47810; ENST00000412193/Downstream/6328;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/9162, chr2-CpG: 16/Downstream/25642
Upstream sequence
GAGGGCCGGGCTGGGCACCAGAGTGGAGACCATAGACCAGGGCAGAGGGCAGGGCCATGAGGGCACTGTGGGCTGTGGATGGAGCTGGCATTTAAGAGGG
Downstream sequence
GAGACCATAGACCAGGGCAGAGGGCAGGGCCGTGCTGGGCACTGTGGGCTGTGGATGGGAGCTGCCATTTATGCTCGGGTGATGGGAATGTGTTAAAAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate