Basic Information
VIS ID
TVIS44021968
Fusion event
HTLV-1-LOC100505736 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.2
Reference genome
GRCh37/hg19
Start
28427964/28205097 (Hg38)
End
28427964/28205097 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
LOC100505736
Nearest miRNA
hsa-mir-1301/Upstream/208648; hsa-mir-10b/Downstream/4327056;
Nearest TSS
ENST00000437798/Upstream/310477; ENST00000460736/Downstream/105362;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/314200, chr2-CpG: 302/Downstream/185000
Upstream sequence
TATTAAAATCAGATTCTGCTGTCATTCTTTTCTATTTTTTTTTGGCCAACCTGGATCACTGGGTCATTGAAAACAACTGTCCTAGATGGTCATTCATGCA
Downstream sequence
CGTAGCTGACTTTCCATGATTTATTGTTGTAATAAGACACTCTCCCATTGATATAGGGAAAGAGGGGCATTTGTTACTGCAGCTTTGCCTAACCTAGCCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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