Basic Information
VIS ID
TVIS44021970
Fusion event
HTLV-1-LINC01317 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
34425470/34200403 (Hg38)
End
34425470/34200403 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC01317
Nearest miRNA
hsa-mir-1301/Upstream/781839; hsa-mir-10b/Downstream/1271002;
Nearest TSS
ENST00000437798/Upstream/133177; ENST00000422558/Downstream/183385;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/472786, chr2-CpG: 191/Downstream/2154851
Upstream sequence
ctggtaagttcagaagttgggatcaaacccaggccttctgattccatgctaaaattctctctttattCTTGAATTGGCAACCTGGCATTTGCTCACATCT
Downstream sequence
TTATCCTTGCTTTATGACTTCCTTTGCTCCTGAAACTACTCTTGAAAATGTATGTTATTTAATTCCTTTTTTTATATTAGAATAGCGTGTTTCCTAATAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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