Basic Information
VIS ID
TVIS44021977
Fusion event
HTLV-1-DCDC2C integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
3805751/3758161 (Hg38)
End
3805751/3758161 (Hg38)
Orient
-
Location type
Intronic
Target gene
DCDC2C
Nearest miRNA
hsa-mir-10b/Downstream/2216501;
Nearest TSS
ENST00000437798/Upstream/32215; ENST00000451101/Downstream/86023;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/53824, chr2-CpG: 54/Downstream/28064
Upstream sequence
ACTACTGATGGAATAAATTGTATGGACTGAAAAGGGAGCAAAATAGACAGAGAAGGGCTGGTCCTGAAAAACTGTGACATTCCCAGTGAGGTGACAGGTG
Downstream sequence
GAGCAGAACAGTGGGACTTGAGAGATGctgtgtatcattgattctatggagggcatgttcccacatcccgacatccctggaacaggtgcatctgacgtcg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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