Basic Information
VIS ID
TVIS44021988
Fusion event
HTLV-1-ACYP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p16.2
Reference genome
GRCh37/hg19
Start
54250377/54023240 (Hg38)
End
54250377/54023240 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2D ; FRA2H
Target gene
ACYP2
Nearest miRNA
hsa-mir-1301/Upstream/174035; hsa-mir-10b/Downstream/1959727;
Nearest TSS
ENST00000437798/Upstream/52132; ENST00000606436/Downstream/59314;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/51887, chr2-CpG: 47/Downstream/92257
Nearby gene
PSME4(-52400) ;
Upstream sequence
AACCTTTCAAAGAATTGTTGTTAATTTCCAGGTGATTATGCTTTTTTGTTGTTGATCATTTCATTTTACATTTTatgtgtgtgtgggttgtgaccatata
Downstream sequence
ttttattattcttgaataatcacccagaagtggaattgctagctcttatggaaagtatgtgtttaactttataagaaatgtcacactAAttttttttaag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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