Basic Information
VIS ID
TVIS44021997
Fusion event
HTLV-1-LOC107984063 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
65251983/65024849 (Hg38)
End
65251983/65024849 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S
Target gene
LOC107984063
Nearest miRNA
hsa-mir-1301/Upstream/499284; hsa-mir-10b/Downstream/1333400;
Nearest TSS
ENST00000437798/Upstream/25401; ENST00000415327/Downstream/5878;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/34771, chr2-CpG: 132/Downstream/31047
Nearby gene
SLC1A4(+983) ;
Upstream sequence
AAGGAGCGCTGATCTGATGAGCTACTTGAACCTGCTCACGGGAACTGTAAATTGTGTCTGAATAGCACAGGCGATGTAGCAGGGAGGACCATGggctgtc
Downstream sequence
tgggttccactcccagctctgctgcttgcttgctgcatgaccctgggcatgataacctctccatggcttagtctcatatttaaaattgggagaccgagtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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