Basic Information
VIS ID
TVIS44022001
Fusion event
HTLV-1-ZNF638 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p13.2
Reference genome
End
71578194/71351064 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1285-2/Upstream/1098059; hsa-mir-10b/Downstream/3739748;
Upstream sequence
GGCAGTGAAGTGTACTATAATGTAGAACATACTGTTCAGTCGTAATCATTGGTAGATTTGAGCAGGAATTTCCAAGTAAATTTTATTTACTTACGTATGG
Downstream sequence
TTGGCAATCACTGTTTCTTCTATTTACTAATGTGATTTATAGATTTAGATTGTAAAGGGTCAGAAGAGAATATACTAACATGGGAAAAAGCTTTGATTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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