Basic Information
VIS ID
TVIS44022016
Fusion event
HTLV-1-LINC00299 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
8259254/8119124 (Hg38)
End
8259254/8119124 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00299
Nearest miRNA
hsa-mir-7158/Upstream/1468685; hsa-mir-10b/Downstream/2073490;
Nearest TSS
ENST00000437798/Upstream/800; ENST00000442864/Downstream/20278;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/90968, chr2-CpG: 56/Downstream/337653
Upstream sequence
GAGCCCAGGAAATAGAGTGATTCCATGGTGTGCTGGGTTGAAGGGCTGCCTGAGCCATTTAGACGCGGGCTGGGTCATGTGGGTGTGTCCTTATCTACCC
Downstream sequence
AGTGCTGTGGGAGGAGCATCTTTCCCTCCCCTGCGAATCCCTGCCAAGCTTCCAAGACCCCTCTCCAAAGCAGCTCCAGGCTTCCTCCAGTCCCCACTAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate