Basic Information
VIS ID
TVIS44022027
Fusion event
HTLV-1-ANKRD20A8P integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
95486762/94821017 (Hg38)
End
95486762/94821017 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA2S
Target gene
ANKRD20A8P
Nearest miRNA
hsa-mir-1285-2/Upstream/6008563; hsa-mir-10b/Downstream/1977261;
Nearest TSS
ENST00000437798/Upstream/3216; ENST00000468063/Downstream/36232;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/85126, chr2-CpG: 117/Downstream/35836
Upstream sequence
GAATAACTCACATTTTATAATTCAAGATTCATGCTTCTGTAGTTGTTAGCACTGGGACTGCCATATAGTGGCTTCTGGAATAAACGCTGTATTGGTTTTC
Downstream sequence
TGTTTTCATTAAGTATCTGTAGCAGCAGAAATACTGTGGCTTTCTATCTGAATCATATGCTTCATTTCTTTGGGGTGGGTAAACAACAAATCAAAAAGAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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