Basic Information
VIS ID
TVIS44022032
Fusion event
HTLV-1-VWA3B integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
98897543/98281080 (Hg38)
End
98897543/98281080 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2A
Target gene
VWA3B
Nearest miRNA
hsa-mir-1285-2/Upstream/1482727; hsa-mir-10b/Downstream/3028370;
Nearest TSS
ENST00000437798/Upstream/35647; ENST00000393503/Downstream/52891;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/193654, chr2-CpG: 114/Downstream/65330
Upstream sequence
TTGCCTTCTGTTAAAGTGCAAATGCCCTGGGAAGGAAGGCACTAATTCGTTTGCCATGGGCCACTCGCTCCCCGCCCCGGAGATGCTGGGCAGGAGTTTG
Downstream sequence
CCACTCCTGATTTCTATTTTCCTGTAAGCTCTTTTCTCATTCTCTCTCCAGTCCATTTTTCAAAGGGATGCAGAGTCTGGATACTTTCTGGGTGGATGAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate