Basic Information
VIS ID
TVIS44022038
Fusion event
HTLV-1-ATP2B2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p25.3
Reference genome
GRCh37/hg19
Start
10529150/10487466 (Hg38)
End
10529150/10487466 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATP2B2
Nearest miRNA
hsa-mir-12127/Upstream/92904; hsa-let-7g/Downstream/5008773;
Nearest TSS
ENST00000440867/Upstream/37686; ENST00000440266/Downstream/18065;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/128564, chr3-CpG: 19/Downstream/18028
Upstream sequence
TAGAAGGAGGATGCTAGGGGTTACCAGGGTCATGAGTCCAGTTGTCAGGTCCTGCCTGGCTTACCTTAGGATCTCCACTGAGGCTGTGGGAAGTCAAGGT
Downstream sequence
CACTGGCAAGGGCAGAGAGCAACTCATCAATTCTCAGCATGAAGCCAGTGGGCCACAAAGGCCTGTGAGTCTTTAGTTCCACAGCCCTGATGGGGGTTGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate