VISDB Viral Integration Site DataBase

VIS ID

TVIS44022041

Fusion event

HTLV-1-BBX integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

q13.12

Reference genome

Start

End

107466362/107747515 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-92b-3p ; hsa-mir-484 ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-4776-5p ; hsa-mir-3688-5p ; hsa-mir-4470 ; hsa-mir-3619-3p ; hsa-mir-298 ; hsa-mir-6089 ; hsa-mir-8076 ; hsa-mir-3163 ; hsa-mir-1277-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-548n ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-93-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-20b-5p ; hsa-mir-6885-3p ; hsa-mir-659-3p ; hsa-mir-29b-2-5p ; hsa-mir-1273e ; hsa-mir-5087 ; hsa-mir-1279 ; hsa-mir-330-3p ; hsa-mir-5197-3p ; hsa-mir-7978 ; hsa-mir-4456 ; hsa-mir-548q ; hsa-mir-4299 ; hsa-mir-9-3p ; hsa-mir-6878-5p ; hsa-mir-4704-3p ; hsa-mir-7849-3p ; hsa-mir-5692a ; hsa-mir-5589-3p ; hsa-mir-6740-3p ; hsa-mir-5585-5p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-676-5p ; hsa-mir-8084 ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429 ; hsa-mir-2054 ; hsa-mir-6873-3p ; hsa-mir-4775 ; hsa-mir-130b-5p ; hsa-mir-4263 ; hsa-mir-4781-3p ; hsa-mir-653-5p ; hsa-mir-575 ; hsa-mir-4676-5p

Nearest miRNA

hsa-let-7g/Upstream/4223399; hsa-mir-12124/Downstream/1855313;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/222032, chr3-CpG: 46/Downstream/180108

Upstream sequence

acagtggtgaaaaataagtcttagaaagtttagctgagctggccaaggtcatgttgtgggtaagtagcagagctgagattcagtctcccagataccctga

Downstream sequence

cccatatccatatgcttcaccaacactgcatcacagctgcctctAACTAGAGAACAGCTTGGAAGGAGTGGTATTGGGAAGAGAGTGAGGGAGTGGCTTC