Basic Information
VIS ID
TVIS44022048
Fusion event
HTLV-1-PLA1A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
119328320/119609473 (Hg38)
End
119328320/119609473 (Hg38)
Orient
+
Location type
Exonic
Target gene
PLA1A
Nearest miRNA
hsa-let-7g/Upstream/2759106; hsa-mir-12124/Downstream/475091;
Nearest TSS
ENST00000440867/Upstream/576; ENST00000488533/Downstream/33079;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/29337, chr3-CpG: 38/Downstream/67669
Upstream sequence
GGCCTCGGCTTCTGAAGCTTTGGGGGAAAGCCTGCCACTGTGAAGCCAGCAGACTCTGTGGCCCACGGGGAACTCACTGTTCCTGCTCTTCTAGGTGCTG
Downstream sequence
GGTGTGTCGGAATCCTCAATCCACATCATTGGTGTTAGCCTGGGGGCCCACGTTGGGGGCATGGTGGGACAGCTCTTCGGAGGCCAGCTGGGACAGATCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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