Basic Information
VIS ID
TVIS44022064
Fusion event
HTLV-1-ACAD9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
128631712/128912869 (Hg38)
End
128631712/128912869 (Hg38)
Orient
+
Location type
UTR3
Target gene
ACAD9
miRNAs that regulate target gene
hsa-mir-615-3p
Nearest miRNA
hsa-let-7g/Upstream/65961; hsa-mir-1224/Downstream/359277;
Nearest TSS
ENST00000440867/Upstream/8493; ENST00000481536/Downstream/22288;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/33009, chr3-CpG: 59/Downstream/80692
Upstream sequence
AGGTTTTGACCTGCAGGCAGTGCTCTCTAACAGGACCATCACAGCTTCTGAACTGAGCCGGAGAGAGAGAATGGAATTGCTGACCCCTGGAACTGGCGGG
Downstream sequence
TATTCTGGTCATTGAGGAGACACCATAGTGGAAACTGGGGCTTATGCTGCTGCCTCCAGGGTGTGAGGTGGGTGGGGACCTGTGTCAGGTGTGGATAGCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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