VISDB Viral Integration Site DataBase

VIS ID

TVIS44022088

Fusion event

HTLV-1-SH3BP5 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

p25.1

Reference genome

Start

End

15382761/15341254 (Hg38)

Orient

-

Location type

UTR5

Target gene

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-103a-3p ; hsa-mir-193b-3p ; hsa-mir-323b-3p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-656-3p ; hsa-mir-7702 ; hsa-mir-568 ; hsa-mir-151a-3p ; hsa-mir-4522 ; hsa-mir-4463 ; hsa-mir-4499 ; hsa-mir-5089-5p ; hsa-mir-6878-3p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-6744-3p ; hsa-mir-4757-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6778-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-212-5p ; hsa-mir-186-3p ; hsa-mir-6849-3p ; hsa-mir-1226-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-106b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-340-5p

Nearest miRNA

hsa-mir-12127/Upstream/4946692; hsa-let-7g/Downstream/154985;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/8552, chr3-CpG: 46/Downstream/86171

Upstream sequence

AGGCCccacctcatctgacttgtgcccacatctcacacctcctctcaccgcccctcctcctcgctcaccctctggcaccacatgggctgtcagctggctc

Downstream sequence

tgtcctcagggcttctgctgtctgcatcgctatctcctccagggcacggctgcctgactccttctcatcatccacatctcagcccaaatgtcacatccat