Basic Information
VIS ID
TVIS44022097
Fusion event
HTLV-1-IQCJ-SCHIP1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q25.33
Reference genome
GRCh37/hg19
Start
159581400/159863611 (Hg38)
End
159581400/159863611 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA3D
Target gene
IQCJ-SCHIP1
Nearest miRNA
hsa-let-7g/Upstream/580877; hsa-mir-1224/Downstream/540977;
Nearest TSS
ENST00000440867/Upstream/10619; ENST00000475932/Downstream/25181;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/98377, chr3-CpG: 52/Downstream/125092
Upstream sequence
gtttttaaataatttgaagggatacaagggcaattctgaaaatctaataaataatatgatctcaactttataaaaaggaaaataatgcacacatatgata
Downstream sequence
aaaactaggaggaaatatactaaaatgttagcaatcatgtctctctaagtggtgggattatgagtgatgtttatattctttAAGCTTTTCTTGATTTGTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate