Basic Information
VIS ID
TVIS44022113
Fusion event
HTLV-1-LINC00578 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q26.32
Reference genome
GRCh37/hg19
Start
177462730/177744942 (Hg38)
End
177462730/177744942 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00578
Nearest miRNA
hsa-let-7g/Upstream/1229791; hsa-mir-1224/Downstream/6141858;
Nearest TSS
ENST00000440867/Upstream/61315; ENST00000434309/Downstream/71923;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/546876, chr3-CpG: 63/Downstream/1326575
Upstream sequence
GAAGTCACCTTATGAAGCATCTACCAGACGAGCCTCTGTGAGTGATTCAGACAAATATAAAAAGCCCTCGAAGGGGTTGCATGATCACATCTTGTACTAG
Downstream sequence
GTTAGTGCCCAAATAACCCAAGCACCCCATGGAATGTGAGAGGTGCCTACAGGGAGAGATGGAATGCCACTGGACTACAGCGGCCAACTCCTCTCACCCC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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