Basic Information
VIS ID
TVIS44022121
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q27.3
Reference genome
GRCh37/hg19
Start
187115827/187398039 (Hg38)
End
187115827/187398039 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA3C
Nearest miRNA
hsa-let-7g/Upstream/611262; hsa-mir-28/Downstream/1290742;
Nearest TSS
ENST00000440867/Upstream/29707; ENST00000440726/Downstream/50806;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/198071, chr3-CpG: 25/Downstream/272087
Nearby gene
RTP4(+26458) ;
Upstream sequence
agttggtggacatatggattggttccattCTGGGACTGCATCAGTGGCAGCATTTAAACAGTGTTTGATTGCTTAGAAAGACTGACAGGACCCAAAGTGA
Downstream sequence
CAATGCTTATAAAGGAGACAAGAACATAGCAATGTTATTCAATTAAGAACCTCAGGCACTTCCTCTCACATTCTCCACAGTCAAGAAGGTTGACCAAGAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate