Basic Information
VIS ID
TVIS44022146
Fusion event
HTLV-1-CLASP2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
33599771/33558279 (Hg38)
End
33599771/33558279 (Hg38)
Orient
+
Location type
Intronic
Target gene
CLASP2
miRNAs that regulate target gene
hsa-mir-210-3p
Nearest miRNA
hsa-mir-12127/Upstream/1051890; hsa-let-7g/Downstream/2186197;
Nearest TSS
ENST00000440867/Upstream/13168; ENST00000430877/Downstream/1062;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/116907, chr3-CpG: 86/Downstream/159435
Upstream sequence
aagtcctcaaaaccctctctggaagaatgaacaggctttcttcttgtgtctctttctcctggatgcatcctcaatcttggcaaactaaacctctaaattg
Downstream sequence
attgagacttgtctcagacacttttcggtttacaAAGTCAGCCCTGATAAGAAACATAATTGTGATTCTGAGGCACAATTGCATTCAGAAACTTAAGGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate