Basic Information
VIS ID
TVIS44022151
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
39616989/39575498 (Hg38)
End
39616989/39575498 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/437232; hsa-let-7g/Downstream/4538714;
Nearest TSS
ENST00000440867/Upstream/73283; ENST00000475082/Downstream/233416;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/72766, chr3-CpG: 136/Downstream/233771
Upstream sequence
TGTTCTTAGTAGGGAAAACTGAATATTTTTCTGAAGTGTTTGTGCTGTTGGCCTTCTGTTTATGTTCTTTCACAGGTTGTGATAGTTGGAAAATGGATGA
Downstream sequence
GCTTGAAGCTGGTAAAAACAAGAATGGAATCCAATCAAAAGAGTTTAGATCAATTGATTTTACTTCTCTTTGAACTTTGCTTAACAGAAAAATGTGGGCG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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