Basic Information
VIS ID
TVIS44022154
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
40962762/40921271 (Hg38)
End
40962762/40921271 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12127/Upstream/1783005; hsa-let-7g/Downstream/3192941;
Nearest TSS
ENST00000440867/Upstream/155064; ENST00000426215/Downstream/50307;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/305367, chr3-CpG: 153/Downstream/277400
Nearby gene
CTNNB1(+278180) ;
Nearest cancer related gene
CTNNB1(OG, +278180) ;
Upstream sequence
AAAGGAGAAGGAGAGCACCCTCAAATGTAGAATGTAATAAAGtgaggactaaactctgatctttttcttctcttgcccaaattcctatctaaggggactg
Downstream sequence
gagagtcataccctacaaaccataaaatctcatcagaggagtttcatttaaccctatataatgtggcctgctttccaatgttgactctggcacaatacca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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