Basic Information
VIS ID
TVIS44022174
Fusion event
HTLV-1-ADAMTS9-AS2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
64683905/64698229 (Hg38)
End
64683905/64698229 (Hg38)
Orient
-
Location type
ncRNA_intronic
Target gene
ADAMTS9-AS2
Nearest miRNA
hsa-let-7g/Upstream/4080359; hsa-mir-12124/Downstream/2527235;
Nearest TSS
ENST00000440867/Upstream/10229; ENST00000481004/Downstream/476729;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/9948, chr3-CpG: 63/Downstream/658299
Nearest cancer related gene
ADAMTS9-AS2(TSG, No orient, 0)
Upstream sequence
aactatgactcaaaatccacaagccgtaaaagaaaaaaaatgaaatatttaactgtattataaaacaaacaaattctgcatgataagaaacattatgtct
Downstream sequence
tggcccattttgtgttgctgtaatagaataccacagagtgggtaatgtatagtgaacgggaatttattggcttatagttctggagactggtaagtccaat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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