Basic Information
VIS ID
TVIS44022180
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
69696525/69647374 (Hg38)
End
69696525/69647374 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/598339; hsa-mir-12124/Downstream/1894596;
Nearest TSS
ENST00000440867/Upstream/56033; ENST00000461511/Downstream/92061;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/104475, chr3-CpG: 78/Downstream/91958
Nearby gene
MITF(+92061) ;
Nearest cancer related gene
MITF(OG, +92061) ;
Upstream sequence
GTGGTGGGTTATGAGTAATTTAAGTTTTTAAAGCATTTCCCAATTCTGGTTGTGCTAGCTACTCAAGATGAATATCAGGATGCAGCACAGTTATATTACA
Downstream sequence
GTGGGGACAACCTTGAAACCCTTCTAATTTAAATTTTTAAAGTACATTTATTTGCCAGTTCTACTGTTGGAAACGTTACAGTGGTGTCCCTATCATCCGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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