Basic Information
VIS ID
TVIS44022188
Fusion event
HTLV-1-LINC00971 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
84795550/84746399 (Hg38)
End
84795550/84746399 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LINC00971
Nearest miRNA
hsa-let-7g/Upstream/5238430; hsa-mir-12124/Downstream/639311;
Nearest TSS
ENST00000440867/Upstream/2760247; ENST00000488348/Downstream/123176;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1938306, chr3-CpG: 48/Downstream/212734
Upstream sequence
AATTTTGTAAATGTATCTCTTATATTAAGAATCCCCTCCTGAAAGGAAAAAATTTAGTCCTGTAATTCTTAGACTCTTCTGATAGCTCAGACTAGTGTGG
Downstream sequence
TTAGAAAGCACTAGGGTGCTATACAGTGCCAAAAACATCTTTTTAAATACAATTTTCTTGTATATATTTATGTAGAAAAACATAACGGTGAACATACATA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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