VISDB Viral Integration Site DataBase

VIS ID

TVIS44022190

Fusion event

HTLV-1-CADM2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr3

Cytoband

p12.1

Reference genome

Start

End

85384769/85335619 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-624-3p ; hsa-mir-1277-5p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-410-3p ; hsa-mir-1273e ; hsa-mir-943 ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4766-5p ; hsa-mir-6074 ; hsa-mir-4778-5p ; hsa-mir-512-3p ; hsa-mir-888-3p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-526b-3p ; hsa-mir-93-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-106b-5p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520a-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520e ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302e ; hsa-mir-520d-3p ; hsa-mir-302a-3p ; hsa-mir-302d-3p ; hsa-mir-5704 ; hsa-mir-4529-5p ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-3913-3p ; hsa-mir-6719-3p ; hsa-mir-489-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-203a-3p ; hsa-mir-627-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-195-3p

Nearest miRNA

hsa-let-7g/Upstream/5827650; hsa-mir-12124/Downstream/50091;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/375933, chr3-CpG: 78/Downstream/1654841

Nearest cancer related gene

CADM2(TSG, No orient, 0)

Upstream sequence

aattattagcatattcatcatctcagatatttatcacttttttttttgttgaggacattcaaaatcctcccttctagctatattgaaatatacaatatgt

Downstream sequence

tattgGTTTTTCTCTAACTCAGTGTTTGAAAATGATATAACAAAGTTTATAGCTTCTGCCTTTCTATTTGTATTTAATAATCAGCTTCTTCTGTGAGATG