Basic Information
VIS ID
TVIS44022196
Fusion event
HTLV-1-PSMC1P6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
87679847/87630697 (Hg38)
End
87679847/87630697 (Hg38)
Orient
-
Location type
Intronic
Target gene
PSMC1P6
Nearest miRNA
hsa-let-7g/Upstream/404420; hsa-mir-12124/Downstream/8729267;
Nearest TSS
ENST00000440867/Upstream/354110; ENST00000319595/Downstream/162932;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/403261, chr3-CpG: 66/Downstream/161949
Nearby gene
HTR1F(+351879) ;
Upstream sequence
TAAGTGTTGGATCCTAAGTTTCTATTTGGTTTGTGGCTATGATAACTTTAATATCTCCCCTTGAATCAGATCCATGCAACTGGTTCAACAGTTCCAACAT
Downstream sequence
TGTTCACTAAATTTCTCTCTCACCACCAAAATTTGAGTCATAGTTTTTCCCAATGGCATCAATTTCATCAATAAACATGATGAAAGGTGCATATTCTTCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate