Basic Information
VIS ID
TVIS44022213
Fusion event
HTLV-1-chr3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
99238134/99519290 (Hg38)
End
99238134/99519290 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105374005 ; LOC105374007
Nearest miRNA
hsa-let-7g/Upstream/3159251; hsa-mir-12124/Downstream/445024;
Nearest TSS
ENST00000440867/Upstream/18943; ENST00000462011/Downstream/7823;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/617238, chr3-CpG: 43/Downstream/298479
Nearby gene
MIR548G(No orient, 35019)
Upstream sequence
tgactctgtggagccaatctaccagcctagactgttaataaactgagaaataaacttttatcttgtttaagccactcttactgatggtttctgttagacc
Downstream sequence
agctgaacctttaattaatacGTTTATCTTCCCTAATCACTCTTTAACATATGTTGACATTTAGATACCATTGACAGTTCTCTATTGCCTAcagaatgaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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