Basic Information
VIS ID
TVIS44022216
Fusion event
HTLV-1-RNF212 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
1070148/1076360 (Hg38)
End
1070148/1076360 (Hg38)
Orient
-
Location type
Intronic
Target gene
RNF212
Nearest miRNA
hsa-mir-571/Upstream/726108; hsa-mir-12113/Downstream/910024;
Nearest TSS
ENST00000502981/Upstream/2606; ENST00000504969/Downstream/5243;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/6189, chr4-CpG: 31/Downstream/19701
Upstream sequence
CAGGCCTGGAGCAGCAAGGGTGGAGGAGGAAGGAAAAGAACCAATCCCCTCTGGGCGGGCCCAGCTGTGCCCCAGGCGCTGTCATGGGATGGCGCTGGCT
Downstream sequence
TTGCTTCTCCGAGTCCACCCAATGAGAGACCCTTGCACTGTGGCCCTCCCTCTGACGAGCCTTTGGGGCAGGAACCCCACCAAGAGCACCCCCGATAATG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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