VISDB Viral Integration Site DataBase

VIS ID

TVIS44022241

Fusion event

HTLV-1-HHIP integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

q31.21

Reference genome

Start

End

145568446/144647294 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-526b-5p ; hsa-mir-5186 ; hsa-mir-570-3p ; hsa-mir-1273e ; hsa-mir-155-5p ; hsa-mir-3653-3p ; hsa-mir-548ax ; hsa-mir-548ao-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-4723-5p ; hsa-mir-5698 ; hsa-mir-3175 ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6797-5p ; hsa-mir-1249-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4510 ; hsa-mir-4419a ; hsa-mir-6770-5p ; hsa-mir-6794-5p ; hsa-mir-4716-3p ; hsa-mir-4756-5p ; hsa-mir-4739 ; hsa-mir-1321 ; hsa-mir-4779 ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-3941 ; hsa-mir-5011-5p ; hsa-mir-4643 ; hsa-mir-5580-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-4789-5p ; hsa-mir-574-5p ; hsa-mir-223-5p ; hsa-mir-297 ; hsa-mir-466 ; hsa-mir-6867-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-4789-3p ; hsa-mir-6507-5p ; hsa-mir-186-5p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-4753-3p ; hsa-mir-302a-5p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-6818-3p ; hsa-mir-4684-5p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-5699-3p ; hsa-mir-4421 ; hsa-mir-339-5p ; hsa-mir-3613-3p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-6732-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-200b-5p ; hsa-mir-200a-5p ; hsa-mir-656-3p ; hsa-mir-410-3p ; hsa-mir-5692b ; hsa-mir-5692c ; hsa-mir-369-3p ; hsa-mir-1277-5p ; hsa-mir-4662a-3p ; hsa-mir-6760-5p

Nearest miRNA

hsa-mir-12113/Upstream/1303759; hsa-mir-1305/Downstream/1761289;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/1174, chr4-CpG: 59/Downstream/450717

Upstream sequence

AGACGTTTCTGCGGTACCCGCACCCTGGGCTGGGTAAATATTTTAAAAGAATCGCGATGAACAGTGTGTTTTGGATCGAATGGGGCATTGGCTGCGGTGA

Downstream sequence

AACTGTAAATTAAGGTGGCTGTGGTTTCCGGCTTATTTTTCTAGGGTAAAAAGATTTGTGCTGTTTTCTCCACGTGCTCGGTTAGGGAGAGGATTGAATC