Basic Information
VIS ID
TVIS44022242
Fusion event
HTLV-1-ANAPC10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
145976607/145055455 (Hg38)
End
145976607/145055455 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANAPC10
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-12113/Upstream/1711920; hsa-mir-1305/Downstream/1353128;
Nearest TSS
ENST00000502981/Upstream/203883; ENST00000502586/Downstream/41927;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/409335, chr4-CpG: 59/Downstream/42556
Upstream sequence
gagactagcctgcccaaaatggtgaaaccctgtctacactaaaaatacaaaagttagccgggcatggtggtgtgtgcctgtagtcccagctactcaggag
Downstream sequence
gctgaggcatgagaatcacttgaacccaggatgcagaggttgtagtgagccaatatcacgtcactgcactccagcctgggtgacagagctagacactgtc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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