Basic Information
VIS ID
TVIS44022247
Fusion event
HTLV-1-LOC101929095 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
p15.32
Reference genome
GRCh37/hg19
Start
15064899/15063275 (Hg38)
End
15064899/15063275 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA4D
Target gene
LOC101929095
Nearest miRNA
hsa-mir-12113/Upstream/1435318; hsa-mir-12115/Downstream/5465000;
Nearest TSS
ENST00000502981/Upstream/9142; ENST00000510958/Downstream/164685;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/58138, chr4-CpG: 145/Downstream/591466
Upstream sequence
CACATTAAAAGACTATTTTGGGGACAGGGAAGCTGGTTAATTAATACCGATTGACTAGACCATGCATGCTAGAAGTAGTCCTCAATGTAATTACCCAACC
Downstream sequence
GTCTCATTTAGAAAAGAAATGCAGCATAGGTTCAGTTCACAAATGCAGAGTAGGTTTTTTTTGTTTGTTTGCATTGCTACTTAAAAGGTTGCCAAAAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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