Basic Information
VIS ID
TVIS44022253
Fusion event
HTLV-1-TMEM144 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q32.1
Reference genome
GRCh37/hg19
Start
159141961/158220809 (Hg38)
End
159141961/158220809 (Hg38)
Orient
-
Location type
Intronic
Target gene
TMEM144
Nearest miRNA
hsa-mir-12113/Upstream/5684293; hsa-mir-1305/Downstream/907993;
Nearest TSS
ENST00000502981/Upstream/9543; ENST00000512272/Downstream/12227;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/10225, chr4-CpG: 94/Downstream/450656
Upstream sequence
tgccattaCAATTATTTTATTAATAACATTTATGTTCAATTACTGTTTCCCTGTTGGGTATTTGTTGCCCAACTTTATGTTACAGTAGGCAGTGCACCTG
Downstream sequence
AGGAACCCTGTAGCTCAATTTGAACTTGGTCTGTAGCAGGGAAATTCAAGAACTCTTCCCGTAGTGCATCTAGGCTCCCTTCTATGTTTCTCTGCTAAGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate