VISDB Viral Integration Site DataBase

VIS ID

TVIS44022267

Fusion event

HTLV-1-LETM1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p16.3

Reference genome

Start

End

1821083/1819356 (Hg38)

Orient

+

Location type

Exonic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-877-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-8085 ; hsa-mir-6878-5p ; hsa-mir-6731-5p ; hsa-mir-661 ; hsa-mir-4524a-3p ; hsa-mir-3192-5p ; hsa-mir-6849-3p ; hsa-mir-766-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-508-5p ; hsa-mir-122-3p ; hsa-mir-1272 ; hsa-mir-1827 ; hsa-mir-3675-3p ; hsa-mir-4293 ; hsa-mir-4709-3p ; hsa-mir-4722-5p ; hsa-mir-520f-5p ; hsa-mir-6746-5p ; hsa-mir-6771-3p ; hsa-mir-6771-5p ; hsa-mir-6808-5p ; hsa-mir-6840-3p ; hsa-mir-6893-5p ; hsa-mir-7846-3p ; hsa-mir-940 ; hsa-mir-1262 ; hsa-mir-1273g-3p ; hsa-mir-3664-5p ; hsa-mir-4522 ; hsa-mir-4701-3p ; hsa-mir-4742-3p ; hsa-mir-4793-3p ; hsa-mir-542-3p ; hsa-mir-6736-5p ; hsa-mir-6742-3p ; hsa-mir-6776-5p

Nearest miRNA

hsa-mir-571/Upstream/1469104; hsa-mir-12113/Downstream/167028;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/13024, chr4-CpG: 18/Downstream/7505

Upstream sequence

GTATTATGTATACTTTTGGGGCCAGTACAGCGATTTTACTCTTCTTGCAGTCTCAGAGTCCAGGGAGCAAATCCCACCCACCTCGCTGTAGTCCTGCACA

Downstream sequence

TCCTCCTTCAGCAGCTCCAGCTCCTCCTTCTCCTTGGTGAGTGACTTCTTCTGCTCCTGCAGCTTAGAGCAGGCATCGCTGAGGATGTCGATTTCCTCCT