VISDB Viral Integration Site DataBase

VIS ID

TVIS44022285

Fusion event

HTLV-1-ADD1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p16.3

Reference genome

Start

End

2854564/2852837 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-221-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-513a-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-3681-3p ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-4684-5p ; hsa-mir-6868-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-3143 ; hsa-mir-27a-5p ; hsa-mir-942-5p ; hsa-mir-520f-5p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-660-3p ; hsa-mir-543 ; hsa-mir-222-5p ; hsa-mir-298 ; hsa-mir-3158-5p ; hsa-mir-320a ; hsa-mir-320b ; hsa-mir-320c ; hsa-mir-320d ; hsa-mir-33b-3p ; hsa-mir-3614-3p ; hsa-mir-3619-3p ; hsa-mir-371a-3p ; hsa-mir-371b-3p ; hsa-mir-4429 ; hsa-mir-4473 ; hsa-mir-4671-3p ; hsa-mir-4724-3p ; hsa-mir-515-3p ; hsa-mir-519e-3p ; hsa-mir-591 ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-193b-5p ; hsa-mir-3074-5p ; hsa-mir-3170 ; hsa-mir-4722-3p ; hsa-mir-4731-5p ; hsa-mir-6727-3p ; hsa-mir-6743-3p ; hsa-mir-6747-3p ; hsa-mir-6855-5p ; hsa-mir-7152-5p ; hsa-mir-7155-5p

Nearest miRNA

hsa-mir-4800/Upstream/602681; hsa-mir-12113/Downstream/3070438;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/8306, chr4-CpG: 17/Downstream/73489

Upstream sequence

acccaggctgaagtgcagcggtgcgatcttggctctcactgcagccttgacctcgtgggcccgagcagtcctcccacccagcttcctgagcagctgggcc

Downstream sequence

tgcagacccaccccaccacacccagctaactaaaaaaattttttttttagtagagccaaggccttgctatgttgcccaggcaggcctGAAGGTGCTTTTA