VISDB Viral Integration Site DataBase

VIS ID

TVIS44022292

Fusion event

HTLV-1-LRPAP1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr4

Cytoband

p16.3

Reference genome

Start

End

3519162/3517435 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-197-3p ; hsa-mir-3659 ; hsa-mir-574-5p ; hsa-mir-138-2-3p ; hsa-mir-3691-3p ; hsa-mir-3174 ; hsa-mir-140-3p ; hsa-mir-6501-3p ; hsa-mir-95-5p ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-4796-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548ah-5p ; hsa-mir-4668-3p ; hsa-mir-3609 ; hsa-mir-7977 ; hsa-mir-6721-5p ; hsa-mir-383-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-4454 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-4716-5p ; hsa-mir-6767-3p ; hsa-mir-4781-3p ; hsa-mir-767-5p ; hsa-mir-342-3p ; hsa-mir-1228-3p ; hsa-mir-7153-3p ; hsa-mir-649 ; hsa-mir-1184 ; hsa-mir-3613-3p ; hsa-mir-371b-5p ; hsa-mir-373-5p ; hsa-mir-4293 ; hsa-mir-4325 ; hsa-mir-4418 ; hsa-mir-4461 ; hsa-mir-509-3-5p ; hsa-mir-509-5p ; hsa-mir-5186 ; hsa-mir-616-5p ; hsa-mir-7156-3p ; hsa-mir-7703

Nearest miRNA

hsa-mir-4800/Upstream/1267279; hsa-mir-12113/Downstream/2405840;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/2318, chr4-CpG: 44/Downstream/402

Upstream sequence

CCTGCTGTCTTATCAccatgagggcacagatgccatctcctggcggctgctgtctcctcgagcctagagcagtgcctggcgtgcagctggtgctcagtgt

Downstream sequence

gcacgtggaggatgaGGTACAGAATCGGAAGCTGCGTGAGTGAGGCCAGCAGGCTTCTGGTACACCCTGCACAAGGCTCTGGCCCGGGTACGGGGCAAGA